Principal Investigator: Dr. Eugene Boland
Affiliation: Techshot, Inc.
Techshot is proposing to complete the Preliminary Design Review for a Space-based, automated tissue and organ printing system capable of culturing a defined heterogeneous cell population within the printed tissue prior to implantation. Once completed, this system would function as a bioprinter capable of personalized medical treatment of either earth-based or on orbit personnel with minimal intervention until application or surgical implantation.

Principal Investigator: Dr. Alberto Goenaga
Affiliation: DexMat
Carbon nanotube (CNT) technology allows for lighter weight cables that have electromagnetic interference (EMI) benefits over conventional metallic coaxial cables that use a tin-copper shielding braid. Research in low Earth orbit will accelerate the near-term insertion of CNT cables in satellite systems, with a long-term potential for a two-thirds weight savings for CNT coax cables and power harnesses. Exposing this experiment to the extreme conditions on the ISS will provide long-term performance data and showcase DexMat’s ability to design and implement the technology on spacecraft. The successful completion of this in-orbit testing will raise the Technology Readiness Level of the products (a Department of Defense requirement for adoption of new technologies by the aerospace industry).

Principal Investigator: Dr. Dmitry Starodubov
Affiliation: FOMS Inc.
This project seeks to demonstrate the technical and commercial feasibility of in-orbit manufacturing of optical fibers for data transmission. Fluoride optical fibers have demonstrated a 10- to 100-fold signal loss reduction compared with traditional silica optical fibers, which could dramatically improve the cost and efficiency of communications systems and the internet. However, imperfections that occur during manufacturing on Earth prevent fluoride optical fibers from achieving this reduction in signal loss. Such imperfections appear to be reduced in microgravity, and this project will test ISS capabilities for in-orbit production of ZBLAN optical fibers, a type of fluoride optical fibers.

Principal Investigator: Dan O’Connell
Affiliation: HNu Photonics
Deliver an ultraportable, remote-controlled, automated microfluidics platform for general biological interrogations and planned stem cell research investigations on the ISS.

Principal Investigator: Phoebe Henson
Affiliation: Honeywell International
The goal of this project is to show CO2 absorption by ionic liquid in a spray scrubber and demonstrate the ability to separate the air-liquid mixture in microgravity. This liquid system utilizes spray scrubbing to achieve high surface area between the gaseous CO2 and the liquid absorbent.

Principal Investigator: Steve Altemus
Affiliation: Intuitive Machines
Test a Terrestrial Return Vehicle that addresses the need for priority small-payload return from the ISS. With approximately 30 liters of downmass capability per return flight, this technology should attract increased use of the ISS as an in-orbit laboratory and improve the commercialization of in-orbit experiments for terrestrial benefit.

Principal Investigator: Dr. Robert Applegate
Affiliation: Novopyxis
Improve a patent-pending device, Droplette, for drug delivery directly through skin contact. Droplette can deliver drug molecules up to 60% larger than current topical treatments deep into the skin over broad or uneven surface areas. By studying how the drugs penetrate and spread once they have entered a matrix mimicking human skin, the company may be able to improve the accuracy of drug delivery. Performing these studies in the absence of gravity will give a more accurate representation of how this drug penetration process works in the human body.

Principal Investigator: Hans-Juergen Zachrau
Affiliation: AIRBUS DS Space Systems, Inc.
This project will utilize the unique radiation profile of the ISS to test a novel radiation detection technology that offers the capability to monitor radiation levels from all directions and in real time.

Principal Investigator: Hans-Juergen Zachrau
Affiliation: AIRBUS DS Space Systems, Inc.
This project will use existing SPHERES hardware to examine active steering of a passive body which contains liquid in space.

Principal Investigator: Dr. Supriya Jaiswal
Affiliation: Astrileux Corporation
Develop new smaller Extreme Ultraviolet (EUV) optics which will provide the foundation for optical systems used in solar radiation imaging, ground based telescopes, and satellites. These optics will enable illumination systems with higher resolution and more compact design. The long term exposure to the EUV radiation environment of space allows for accelerated degradation testing of these optical materials.