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Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First)

Higashibata, A., et al. (2007). "Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First)." Microgravity Sci Technol 19 5-6: 159-163

The first International Caenorhabditis elegans Experiment (ICE-First) was carried out using a Russian Soyuz spacecraft from April 19-30, 2004. This experiment was a part of the program of the DELTA (Dutch Expedition for Life science Technology and Atmospheric research) mission, and the space agencies that participate in the International Space Station (ISS) program formed international research teams. A Japanese research team that conducted by Japan aerospace Exploration Agency (JAXA) investigated the following aspects of the organism: (1) whether meiotic chromosomal dynamics and apoptosis in the germ cells were normal under microgravity conditions, (2) the effect of the space flight on muscle cell development, and (3) the effect of the space flight on protein aggregation. In this article, we summarize the results of these biochemical and molecular biological analyses.

Related URLs:
http://www.ncbi.nlm.nih.gov/pubmed/19513185

ISSN: 0938-0108 (Print) 0938-0108 (Linking)

DOI: 10.1007/BF02919473

PMCID: 2693377

Accession Number: 19513185

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Tags: Apoptosis, Biochemistry, Caenorhabditis elegans, Germ Cells, International Space Station, Meiotic chromosomal dynamics, Microgravity, Model organisms, Molecular biology, Muscle Cells