The Constrained Vapor Bubble (CVB) experiment was run in the microgravity environment of the International Space Station as part of the Increment 23-24 which ended in September 2010. Here we present preliminary results which indicate significant differences in the operation of the CVB heat pipe in the micro-gravity environment as compared to the Earth's gravity. The temperature profile data along the heat pipe indicate that the heat pipe behavior is affected favorably by increased capillary flow and adversely by the absence of convective heat transfer as a heat loss mechanism. Image data of the liquid profile in the grooves of the heat pipe indicate that the curvature gradient is considerably different from that on Earth. An initial discussion of the data collected is presented.